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Description
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | ACACB |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3E8 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant ACACB. |
| Formulation | ascites with no preservative |
| Gene | ACACB |
| Gene Accession No. | NM_001093 |
| Gene Alias | ACC2/ACCB/HACC275 |
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