ACE, Mouse, Clone: 3C5, Abnova™

Mouse monoclonal antibody raised against ACE.

Supplier:  Abnova Corporation MAB5228

Catalog No. 89-112-176

Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. [provided by RefSeq

Specifications

• Antigen: ACE
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In tissue culture supernatant (0.09% sodium azide)
• Gene Alias: ACE1, CD143, DCP, DCP1, MGC26566
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry, Western Blot
• Clone: 3C5
• Description: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
• Gene: ACE
• Gene Symbols: ACE
• Immunogen: Denatured human ACE.
• Regulatory Status: RUO
• Gene ID (Entrez): 1636
• Form: Liquid