ACLY, Mouse, Monoclonal Antibody, Abnova™

Catalog No.	Quantity
89-109-349	100 μg

Catalog No. 89-109-349 Supplier Abnova Corporation Supplier No. MAB11167

Description

Mouse monoclonal antibody raised against partial recombinant protein of ACLY.

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Specifications

• Antigen: ACLY
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant protein of ACLY.
• Dilution: ELISA (1:5000-1:20000) Western Blot (1:100-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (1% BSA, 50% glycerol, 0.02% sodium azide)
• Gene: ACLY
• Gene Alias: ACL/ATPCL/CLATP
• Gene Symbols: ACLY
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to C-terminus of human ACLY.
• Purification Method: Protein G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 47
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid