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HLA-G, Mouse, FITC, Clone: Hs-14, Abnova™

Catalog No. 89111857 Shop All Abnova Corporation Products
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Catalog No. 89-111-857 Supplier Abnova Corporation Supplier No. MAB4490
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Description

Mouse monoclonal antibody raised against native ACRV1.

This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for <1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. [provided by RefSeq

Specifications

Antigen HLA-G
Applications Flow Cytometry, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone Hs-14
Conjugate FITC
Description Mouse monoclonal antibody raised against native ACRV1.
Dilution Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% BSA, 0.09% sodium azide)
Gene ACRV1
Gene Alias D11S4365/SP-10/SPACA2
Gene Symbols ACRV1
Host Species Mouse
Immunogen Native purified human ACRV1.
Quantity 50 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56
Test Specificity This antibody reacts with a 220 KDa testis-specific human intra-acrosomal protein associated with the membranes of the acrosomal vesicle.
Target Species Human, Mouse
Content And Storage Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgM
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