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ACVR1, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89104038 Shop All Abnova Corporation Products
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89-104-038 50 μL
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Catalog No. 89-104-038 Supplier Abnova Corporation Supplier No. H00000090A01
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Mouse polyclonal antibody raised against a partial recombinant ACVR1.

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq

Sequence: MEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF

Specifications

Antigen ACVR1
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant ACVR1.
Formulation 50% glycerol
Gene ACVR1
Gene Accession No. BC033867
Gene Alias ACTRI/ACVR1A/ACVRLK2/ALK2/FOP/SKR1/TSRI
Gene Symbols ACVR1
Host Species Mouse
Immunogen ACVR1 (AAH33867, 21 a.a. to 120 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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