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Description
This gene encodes class I alcohol dehydrogenase, alpha subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. This gene is monomorphic and predominant in fetal and infant livers, whereas the genes encoding beta and gamma subunits are polymorphic and strongly expressed in adult livers. [provided by RefSeq
Specifications
Specifications
| Antigen | ADH1A |
| Applications | Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 1.00E+05 |
| Conjugate | Unconjugated |
| Description | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| Formulation | In PBS, pH 7.4 (0.09% sodium azide) |
| Gene | ADH1A |
| Gene Alias | ADH1 |
| Gene Symbols | ADH1A |
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