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CD11c Mouse anti-Human, Unlabeled, Clone: 3.9, BD

Catalog No. BDB565805 Shop All BD Biosciences Products
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BDB565805 0.1 mg
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Catalog No. BDB565805 Supplier BD Biosciences Supplier No. 565805
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Description

Mouse Monoclonal Antibody

The 3.9 monoclonal antibody specifically binds to CD11c, which is also known as Integrin alpha X ( α X Integrin/ITGAX), or p150,95 Integrin alpha chain. CD11c is a ∽150 kDa type I transmembrane glycoprotein. It is expressed on monocytes, macrophages, granulocytes, NK cells, dendritic cells, and subsets of B and T cells. It associates with CD18 (Integrin beta 2/ β 2 Integrin) to form the CD11c/CD18 complex, which is also known as p150,95 Integrin, or the Type 4 Complement Receptor (CR4). CD11c/CD18 binds fibrinogen and reportedly serves as a receptor for iC3b and ICAM-1/CD54. CD11c/CD18 functions as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium. The 3.9 monoclonal antibody crossreacts with Rhesus macaque leucocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11c
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone 3.9
Concentration 0.5mg/mL
Conjugate Unconjugated
Description ITGAX; AlphaX Integrin; Axb2; Integrin alpha-X; CR4; SLEB6; p150,95 alpha
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human monocytes and synovial cells
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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