Amyloid-beta 1-40, Mouse, Clone: BDI350, Abnova™

Catalog No.	Quantity
89-111-651	100 μg

Catalog No. 89-111-651 Supplier Abnova Corporation Supplier No. MAB3913

Description

Mouse monoclonal antibody raised against synthetic peptide of Amyloid-beta 1-40.

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: Amyloid-beta 1-40
• Applications: ELISA, Immunocytochemistry, Western Blot
• Classification: Monoclonal
• Clone: BDI350
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of Amyloid-beta 1-40.
• Dilution: ELISA (0.1 ug/mL) Western Blot (1 ug/mL HRP/ECL detection) Immunocytochemistry (1-10 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 2X PBS (PEG, sucrose, 0.09% sodium azide)
• Gene: APP
• Gene Alias: AAA/ABETA/ABPP/AD1/APPI/CTFgamma/CVAP/PN2
• Gene Symbols: APP
• Host Species: Mouse
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human Amyloid-beta 1-40.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 351
• Test Specificity: Specifically reacts with the C-terminus of human beta Amyloid 1-40. Does not cross-react with beta Amyloid 1-42.
• Target Species: Human
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1