APOB, Mouse, Clone: 1605, Abnova™

Catalog No.	Quantity
89-111-671	1 mg

Catalog No. 89-111-671 Supplier Abnova Corporation Supplier No. MAB4019

Description

Mouse monoclonal antibody raised against native APOB.

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq

Specifications

• Antigen: APOB
• Applications: ELISA, Radioimmune Assays (RIA)
• Classification: Monoclonal
• Clone: 1605
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native APOB.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In 15mM potassium phosphate buffer, 150mM NaCl, pH 7.2 (0.09% sodium azide)
• Gene: APOB
• Gene Alias: FLDB
• Gene Symbols: APOB
• Host Species: Mouse
• Immunogen: Native purified APOB from human serum.
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 338
• Test Specificity: No cross reactivity with Apo A-I or Apo A-II.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b