APOE, Mouse, Clone: 1H4, Abnova™

Catalog No.	Quantity
89-108-675	100 μL

Catalog No. 89-108-675 Supplier Abnova Corporation Supplier No. MAB10490

Description

Mouse monoclonal antibody raised against partial recombinant APOE.

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

• Antigen: APOE
• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 1H4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant APOE.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: APOE
• Gene Alias: AD2/LPG/MGC1571/apoprotein
• Gene Symbols: APOE
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human APOE.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 348
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1