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APOE, Mouse, Clone: WUE-4, Abnova™

Catalog No. 89110968 Shop All Abnova Corporation Products
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89-110-968 100 μL
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Catalog No. 89-110-968 Supplier Abnova Corporation Supplier No. MAB2371
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Description

Mouse monoclonal antibody raised against APOE.

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

Antigen APOE
Applications ELISA, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone WUE-4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against APOE.
Dilution Western Blot (2 ug/mL) Immunohistochemistry (2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris-glycine, 150mM NaCl (0.05% sodium azide)
Gene APOE
Gene Alias AD2/LPG/MGC1571/apoprotein
Gene Symbols APOE
Host Species Mouse
Immunogen Human APOE.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 348
Target Species Human
Content And Storage Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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