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Description
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | ARAP1 |
| Applications | Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | ARAP1-2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant ARAP1. |
| Dilution | Western Blot (2 ug/m) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.09% sodium azide) |
| Gene | ARAP1 |
| Gene Alias | CENTD2/KIAA0782 |
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