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Description
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM
Specifications
Specifications
| Antigen | AURKB |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 5H7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant AURKB. |
| Formulation | ascites with no preservative |
| Gene | AURKB |
| Gene Accession No. | BC009751 |
| Gene Alias | AIK2/AIM-1/AIM1/ARK2/AurB/IPL1/STK12/STK5 |
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