MilliporeSigma™ Mouse anti-AXL, Clone: 7E10,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABC680

Catalog No. MABC680MI

Description

Specifically detects AXL clone: 7E10 in Human samples, and it is validated for Immunocytochemistry, Western Blotting

AXL receptor tyrosine kinase, also known as UFO, JTK11. AXL is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. AXL transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: AXL
• Classification: Monoclonal
• Formulation: Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
• Gene Symbols: AXL; UFO
• Immunogen: Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
• Quantity: 100 μL
• Research Discipline: Apoptosis, Cancer
• Target Species: Human
• Form: Ascites

• Applications: Immunocytochemistry, Western Blot
• Clone: 7E10
• Gene Accession No.: P30530
• Host Species: Mouse
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
• Isotype: IgG1

For Research Use Only