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Description
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq
Specifications
Specifications
| Antigen | BAK1 |
| Applications | ELISA, Immunoprecipitation |
| Classification | Monoclonal |
| Clone | 1E4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant BAK1. |
| Formulation | ascites with no preservative |
| Gene | BAK1 |
| Gene Accession No. | BC004431 |
| Gene Alias | BAK/BAK-LIKE/BCL2L7/CDN1/MGC117255/MGC3887 |
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