BCAM, Mouse, Clone: BRIC221, Abnova™

Mouse monoclonal antibody raised against native BCAM.

Supplier:  Abnova Corporation MAB5244

Catalog No. 89-112-186

Description

Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: BCAM
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (10ul of the suggested working dilution to label 10⁶ cells or 100ul) The optimal working dilution should be determined by the end user.
• Gene: BCAM
• Gene Symbols: BCAM
• Immunogen: Native purified BCAM from human erythrocytes.
• Regulatory Status: RUO
• Gene ID (Entrez): 4059
• Target Species: Human
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Clone: BRIC221
• Description: Mouse monoclonal antibody raised against native BCAM.
• Formulation: In PBS, pH 7.5 (0.09% sodium azide)
• Gene Alias: AU/CD239/LU/MSK19
• Host Species: Mouse
• Quantity: 200 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes a non-polymorphic determinant on both the 85 and 78kD Lutheran (Lu) glycoproteins. BRIC 221 specifically recognizes an epitope in the fourth extracellular domain of Lu glycoprotein. CD239 is expressed by erythrocytes in the peripheral blood.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2b