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BCL2, Mouse, PE, Clone: Bcl2/100, Abnova™

Catalog No. 89108433 Shop All Abnova Corporation Products
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100 Reactions
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89-108-433 100 Reactions
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Catalog No. 89-108-433 Supplier Abnova Corporation Supplier No. MAB10228
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Description

Mouse monoclonal antibody raised against synthetic peptide of BCL2.

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq

Specifications

Antigen BCL2
Applications Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone Bcl2/100
Conjugate PE
Description Mouse monoclonal antibody raised against synthetic peptide of BCL2.
Dilution Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% BSA, 0.09% sodium azide)
Gene BCL2
Gene Alias Bcl-2
Gene Symbols BCL2
Host Species Mouse
Immunogen A synthetic peptide corresponding to amino acids 41-54 of human BCL2.
Purification Method Size-exclusion chromatography purification
Quantity 100 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 596
Test Specificity BCL2, a protooncogen with anti-apoptotic effect, expressed in outer mitochondrial membrane, endoplasmic reticulum and nuclear envelope.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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