BCL2L1, Mouse, Clone: 7B2.5, Abnova™

Mouse monoclonal antibody raised against recombinant BCL2L1.

Supplier:  Abnova Corporation MAB3283

Catalog No. 89-111-311

Description

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq

Specifications

• Antigen: BCL2L1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5 ug/mL) Flow Cytometry (3 ug/10⁶ cells) The optimal working dilution should be determined by the end user.
• Gene: BCL2L1
• Gene Symbols: BCL2L1
• Immunogen: Recombinant protein corresponding to human BCL2L1.
• Regulatory Status: RUO
• Gene ID (Entrez): 598
• Target Species: Human
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: 7B2.5
• Description: Mouse monoclonal antibody raised against recombinant BCL2L1.
• Formulation: In 100mM BBS, pH 8.0
• Gene Alias: BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Human Bcl-xL.
• Content And Storage: Store at 4°C.
• Isotype: IgG3