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BCL2L1, Mouse, Clone: NC1, Abnova™

Catalog No. 89113678 Shop All Abnova Corporation Products
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89-113-678 3 x 1 mL
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Catalog No. 89-113-678 Supplier Abnova Corporation Supplier No. MAB9532

Description

Mouse monoclonal antibody raised against synthetic peptide of BCL2L1.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq

Specifications

Antigen BCL2L1
Applications Immunohistochemistry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone NC1
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against synthetic peptide of BCL2L1.
Dilution Immunohistochemistry (1:20-1:40) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from tissue culture supernatant (0.09% sodium azide)
Gene BCL2L1
Gene Alias BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS
Gene Symbols BCL2L1
Host Species Mouse
Immunogen A synthetic peptide corresponding to amino acids 46-66 of human BCL2L1.
Quantity 3 x 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 598
Target Species Human
Content And Storage Store at 4°C on dry atmosphere. After reconstitution with sterile distilled water store at 4°C for at least two months. For long term storage store at -20°C or below. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG2b
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