BCL2L1, Mouse, PE, Clone: 7B2.5, Abnova™

Catalog No.	Quantity
89-112-493	100 μg

Catalog No. 89-112-493 Supplier Abnova Corporation Supplier No. MAB5861

Description

Mouse monoclonal antibody raised against recombinant BCL2L1.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq

Specifications

• Antigen: BCL2L1
• Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
• Classification: Monoclonal
• Clone: 7B2.5
• Conjugate: PE
• Description: Mouse monoclonal antibody raised against recombinant BCL2L1.
• Dilution: Flow Cytometry (0.3 ug/10⁶ cells) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: BCL2L1
• Gene Alias: BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS
• Gene Symbols: BCL2L1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human BCL2L1.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 598
• Test Specificity: human Bcl-xL (Mr 29 KDa).
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG3