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BCL2L11, Mouse, Clone: 1C2H4, Abnova™

Catalog No. 89111123 Shop All Abnova Corporation Products
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89-111-123 100 μg
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Catalog No. 89-111-123 Supplier Abnova Corporation Supplier No. MAB2751
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Description

Mouse monoclonal antibody raised against recombinant BCL2L11.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq

Specifications

Antigen BCL2L11
Applications Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 1C2H4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant BCL2L11.
Dilution Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene BCL2L11
Gene Alias BAM/BIM/BIM-alpha6/BIM-beta6/BIM-beta7/BOD/BimEL/BimL
Gene Symbols BCL2L11
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 176-280 of human BCL2L11.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10018
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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