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BCL6, Mouse, Clone: LN22, Abnova™

Catalog No. 89113705 Shop All Abnova Corporation Products
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89-113-705 3 x 1 mL
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Catalog No. 89-113-705 Supplier Abnova Corporation Supplier No. MAB9607

Description

Mouse monoclonal antibody raised against partial recombinant BCL6.

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen BCL6
Applications Immunohistochemistry
Classification Monoclonal
Clone LN22
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant BCL6.
Dilution Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.09% sodium azide)
Gene BCL6
Gene Alias BCL5/BCL6A/LAZ3/ZBTB27/ZNF51
Gene Symbols BCL6
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 1-350 near N-terminus of human BCL6.
Quantity 3 x 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 604
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG2b
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