BEST1, Mouse, Clone: E6-6, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of BEST1.

Supplier:  Abnova Corporation MAB2330

Catalog No. 89-110-936

Description

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms

Sequence: KDHMDPYWALENRDEAHS

Specifications

• Antigen: BEST1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: BEST1
• Gene Symbols: BEST1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human BEST1.
• Regulatory Status: RUO
• Gene ID (Entrez): 7439
• Target Species: Human, Pig, Primate
• Form: Liquid

• Applications: Immunofluorescence, Western Blot
• Clone: E6-6
• Description: Mouse monoclonal antibody raised against synthetic peptide of BEST1.
• Formulation: In buffer containing 0.09% sodium azide
• Gene Alias: ARB/BEST/BMD/TU15B/VMD2
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes a band at ∼68 KDa on Western Blot.
• Content And Storage: Store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ