Beta amyloid, Mouse, Clone: AP-5, Abnova™

Catalog No.	Quantity
89-110-458	100 μg

Catalog No. 89-110-458 Supplier Abnova Corporation Supplier No. MAB1495

Description

Mouse monoclonal antibody raised against synthetic peptide of Beta amyloid.

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: Beta amyloid
• Applications: Immunohistochemistry
• Classification: Monoclonal
• Clone: AP-5
• Conjugate: Unconjugated
• Description: amyloid beta (A4) precursor protein
• Formulation: Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)
• Gene: APP
• Gene Alias: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
• Gene Symbols: APP
• Host Species: Mouse
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human Beta amyloid.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 351
• Target Species: Human
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1