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MilliporeSigma™ Mouse anti-BTLA/cd272, Clone: FLO67B,

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MABF269MI 100 μg
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Catalog No. MABF269MI Supplier MilliporeSigma™ Supplier No. MABF269
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Description

Mouse Monoclonal Antibody

Specifically detects BTLA/cd272 clone: FLO67B in Human samples, and it is validated for Immunohistochemistry

The BTLA gene product B- and T-lymphocyte attenuator, also known as cluster of differentiation 272 (CD272), is a T cell coinhibitory receptor of the immunoglobulin superfamily with structural similarity to programmed cell death 1 (PD1) and CTLA4. BTLA is reported to negatively regulate immune responses via interaction with the B7 superfamily costimulatory molecule B7-H4 as well as with tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). Polymorphisms in the BTLA gene have been associated with an increased risk of rheumatoid arthritis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BTLA/cd272
Applications Immunohistochemistry
Classification Monoclonal
Clone FLO67B
Concentration 1mg/mL
Formulation Purified mouse monoclonal IgG1λ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. Q7Z6A9
Gene Symbols BTLA
Host Species Mouse
Immunogen Recombinant protein corresponding to human BTLA/cd272.
Purification Method Protein G Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Inflammation and Immunology
Primary or Secondary Primary
Gene ID (Entrez) NP_001078826
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Form Purified
Isotype IgG1 λ
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For Research Use Only

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