c-MAF Mouse, PE, Clone: T54-853, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565795

Catalog No. BDB565795

Description

The T54-853 monoclonal antibody recognizes c-Maf, a transcription factor that is also known as, MAF, c-Maf protooncogene, or V-maf musculoaponeurotic fibrosarcoma oncogene homolog. c-Maf belongs to the basic leucine zipper (bZIP) family of transcription factors. c-Maf acts as a homodimer or can dimerize with other bZIP transcription factors to either activate or repress the expression of various genes. It plays multiple roles in the differentiation and effector functions of leucocytes, including macrophages, Th2 cells, Th17 cells, and T follicular helper (Tfh) cells. c-Maf drives the expression of IL-10 by activated macrophages, IL-21 by activated Tfh and Th17 cells, and IL-4 by Th2 cells.

Specifications

• Antigen: c-MAF
• Clone: T54-853
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Murine
• Isotype: IgG_2a, κ
• Quantity: 50μg
• Storage Requirements: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry, Immunocytochemistry
• Concentration: 0.2mg/mL
• Description: MAF; v-MAF; MAF; AYGRP; CCA4; CTRCT21
• Format: Affinity Purified
• Immunogen: Human c-MAF Recombinant Protein
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Murine