c-MAF Mouse, PE, Clone: T54-853, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 565795

Catalog No. BDB565795

Description

The T54-853 monoclonal antibody recognizes c-Maf, a transcription factor that is also known as, MAF, c-Maf protooncogene, or V-maf musculoaponeurotic fibrosarcoma oncogene homolog. c-Maf belongs to the basic leucine zipper (bZIP) family of transcription factors. c-Maf acts as a homodimer or can dimerize with other bZIP transcription factors to either activate or repress the expression of various genes. It plays multiple roles in the differentiation and effector functions of leucocytes, including macrophages, Th2 cells, Th17 cells, and T follicular helper (Tfh) cells. c-Maf drives the expression of IL-10 by activated macrophages, IL-21 by activated Tfh and Th17 cells, and IL-4 by Th2 cells.

Specifications

• Antigen: c-MAF
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: MAF; v-MAF; MAF; AYGRP; CCA4; CTRCT21
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human, Mouse
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: T54-853
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human c-MAF Recombinant Protein
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov