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c-MAF Mouse, PE, Clone: T54-853, BD

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BDB565795 50 μg
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Catalog No. BDB565795 Supplier BD Biosciences Supplier No. 565795
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Description

Mouse Monoclonal Antibody

The T54-853 monoclonal antibody recognizes c-Maf, a transcription factor that is also known as, MAF, c-Maf protooncogene, or V-maf musculoaponeurotic fibrosarcoma oncogene homolog. c-Maf belongs to the basic leucine zipper (bZIP) family of transcription factors. c-Maf acts as a homodimer or can dimerize with other bZIP transcription factors to either activate or repress the expression of various genes. It plays multiple roles in the differentiation and effector functions of leucocytes, including macrophages, Th2 cells, Th17 cells, and T follicular helper (Tfh) cells. c-Maf drives the expression of IL-10 by activated macrophages, IL-21 by activated Tfh and Th17 cells, and IL-4 by Th2 cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen c-MAF
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone T54-853
Concentration 0.2mg/mL
Conjugate PE
Description MAF; v-MAF; MAF; AYGRP; CCA4; CTRCT21
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human c-MAF Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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