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C4A, Mouse, Clone: C4D205, Abnova™

Catalog No. 89109640 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-109-640 100 μg
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Catalog No. 89-109-640 Supplier Abnova Corporation Supplier No. MAB11493

Description

Mouse monoclonal antibody raised against C4A.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq

Specifications

Antigen C4A
Applications Immunofluorescence
Classification Monoclonal
Clone C4D205
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against C4A.
Dilution Immunofluorescence (0.5-1.0 ug/mL) The optimal working dilution should be determined by the end user.
Formulation 10mM PBS, 0.05% BSA, and 0.05% Azide
Gene C4A
Gene Alias C4/C4A2/C4A3/C4A4/C4A6/C4S/CO4/CPAMD2/MGC164979/RG
Gene Symbols C4A
Host Species Mouse
Immunogen Recombinant human Complement 4d protein.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 720
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1
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