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CA9, Mouse, Clone: TH22, Abnova™

Catalog No. 89113685 Shop All Abnova Corporation Products
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89-113-685 3 x 1 mL
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Catalog No. 89-113-685 Supplier Abnova Corporation Supplier No. MAB9551

Description

Mouse monoclonal antibody raised against partial recombinant CA9.

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq

Specifications

Antigen CA9
Applications Immunohistochemistry
Classification Monoclonal
Clone TH22
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant CA9.
Dilution Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.09% sodium azide)
Gene CA9
Gene Alias CAIX/MN
Gene Symbols CA9
Host Species Mouse
Immunogen Recombinant protein corresponding to 118 amino acids of human CA9.
Quantity 3 x 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 768
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG2a
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