Cardiac Troponin T Mouse, Alexa Fluor 647, Clone: 13-11, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 565744
The 13-11 monoclonal antibody specifically recognizes Troponin T type 2 (cardiac), encoded by the gene TNNT2 . Troponin T is the tropomyosin-binding subunit of the troponin complex, which also encompasses troponin C and troponin I. This complex regulates muscle contraction in skeletal and cardiac muscle in response to alterations in calcium levels. Troponin T type 2 is solely found in the heart, and genetic alterations in the TNNT2 gene are associated to a series of heart disorders in humans, including hypertrophic cardiomyopathy, dilated cardiomyopathy and left ventricular noncompaction. Cardiac Troponin T can be used as a marker for the identification of cardiomyocytes derived from pluripotent stem cells.
|Cardiac Troponin T|
|Alexa Fluor 647|
|Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence|
|cTnT, Cardiac Muscle Troponin T, Troponin T type 2, TNNT2|
|Rabbit cardiac troponin T Protein|
|Canine, Chicken, Guinea Pig, Human, Murine, Porcine, Rabbit, Rat|
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