Cardiac Troponin T Mouse, Alexa Fluor 647, Clone: 13-11, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565744

Catalog No. BDB565744

Description

The 13-11 monoclonal antibody specifically recognizes Troponin T type 2 (cardiac), encoded by the gene TNNT2 . Troponin T is the tropomyosin-binding subunit of the troponin complex, which also encompasses troponin C and troponin I. This complex regulates muscle contraction in skeletal and cardiac muscle in response to alterations in calcium levels. Troponin T type 2 is solely found in the heart, and genetic alterations in the TNNT2 gene are associated to a series of heart disorders in humans, including hypertrophic cardiomyopathy, dilated cardiomyopathy and left ventricular noncompaction. Cardiac Troponin T can be used as a marker for the identification of cardiomyocytes derived from pluripotent stem cells.

Specifications

• Antigen: Cardiac Troponin T
• Clone: 13-11
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Host Species: Murine
• Isotype: IgG₁, κ
• Quantity: 50μg
• Storage Requirements: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Concentration: 0.2mg/mL
• Description: cTnT, Cardiac Muscle Troponin T, Troponin T type 2, TNNT2
• Format: Affinity Purified
• Immunogen: Rabbit cardiac troponin T Protein
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Canine, Chicken, Guinea Pig, Human, Murine, Porcine, Rabbit, Rat