CASP3, Mouse, Clone: CPP32 4-1-18, Abnova™

Catalog No.	Quantity
89-110-959	200 μL

Catalog No. 89-110-959 Supplier Abnova Corporation Supplier No. MAB2360

Description

Mouse monoclonal antibody raised against full-length recombinant CASP3.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]

Specifications

• Antigen: CASP3
• Applications: Western Blot
• Classification: Monoclonal
• Clone: CPP32 4-1-18
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant CASP3.
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In buffer containing 0.09% sodium azide
• Gene: CASP3
• Gene Alias: CPP32/CPP32B/SCA-1
• Gene Symbols: CASP3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human CASP3.
• Quantity: 200 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 836
• Target Species: Human, Rat
• Content And Storage: Store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a κ