CASP7, Mouse, Clone: 25B881.1, Abnova™

Catalog No.	Quantity
89-112-761	100 μg

Catalog No. 89-112-761 Supplier Abnova Corporation Supplier No. MAB6243

Description

Mouse monoclonal antibody raised against recombinant CASP7.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq

Specifications

• Antigen: CASP7
• Applications: Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 25B881.1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant CASP7.
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: CASP7
• Gene Alias: CMH-1/ICE-LAP3/MCH3
• Gene Symbols: CASP7
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human CASP7.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 840
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1