CASP7, Mouse, Clone: B4-G2, Abnova™

Catalog No.	Quantity
89-113-472	100 μg

Catalog No. 89-113-472 Supplier Abnova Corporation Supplier No. MAB8485

Description

Mouse monoclonal antibody raised against synthetic peptide of CASP7.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq

Specifications

• Antigen: CASP7
• Applications: Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: B4-G2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of CASP7.
• Dilution: Western Blot (0.5-2 ug/mL) Immunoprecipitation (4-10 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 1.5mM thimerosal)
• Gene: CASP7
• Gene Alias: CMH-1/ICE-LAP3/MCH3
• Gene Symbols: CASP7
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to human CASP7.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 840
• Test Specificity: Detects both pro-caspase-7 (34 KDa) and the large subunit of cleaved caspase-7 (19 KDa) in apoptosis cells on SDS-PAGE immunoblots.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1