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CASR, Mouse, Clone: HL 1499, Abnova™

Catalog No. 89110956 Shop All Abnova Corporation Products
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89-110-956 100 μL
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Catalog No. 89-110-956 Supplier Abnova Corporation Supplier No. MAB2357
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Description

Mouse monoclonal antibody raised against partial recombinant CASR.

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq

Specifications

Antigen CASR
Applications ELISA, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone HL 1499
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant CASR.
Dilution ELISA (1:50-1:200) Immunohistochemistry (Frozen sections) (1:50-1:200) RadioEnzymeImmunoassay (1:50-1:200) Western Blot (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In Tris-glycine, 150mM NaCl (0.05% sodium azide)
Gene CASR
Gene Alias CAR/FHH/FIH/GPRC2A/HHC/HHC1/MGC138441/NSHPT/PCAR1
Gene Symbols CASR
Host Species Mouse
Immunogen Recombinant protein corresponding to N-terminus extracellular region of human CASR.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 846
Test Specificity This antibody is specific to Calcium Sensing Receptor protein.
Target Species Human, Mouse, Rabbit, Rat
Content And Storage Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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