CBL, Mouse, Clone: M159, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of CBL.

Supplier:  Abnova Corporation MAB1378

Catalog No. 89-110-394

Description

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq

Specifications

• Antigen: CBL
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user.
• Gene: CBL
• Gene Symbols: CBL
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CBL.
• Regulatory Status: RUO
• Gene ID (Entrez): 867
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: M159
• Description: Mouse monoclonal antibody raised against synthetic peptide of CBL.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene Alias: C-CBL/CBL2/RNF55
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This sequence is highly conserved in rat and mouse c-Cbl.
• Form: Liquid