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Description
This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq]
Specifications
Specifications
| Antigen | CCL5 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 8f64 |
| Concentration | 1 ug/uL |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against full length recombinant CCL5. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In citrate-Tris-HCl, pH7.0 (0.02% Proclin 300) |
| Gene | CCL5 |
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