CCND2, Mouse, Clone: DCS3.1, Abnova™

Catalog No.	Quantity
89-110-668	100 μg

Catalog No. 89-110-668 Supplier Abnova Corporation Supplier No. MAB1852

Description

Mouse monoclonal antibody raised against full-length recombinant CCND2.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq

Specifications

• Antigen: CCND2
• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: DCS3.1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant CCND2.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.08% sodium azide)
• Gene: CCND2
• Gene Alias: KIAK0002/MGC102758
• Gene Symbols: CCND2
• Host Species: Mouse
• Immunogen: Recombinant His fusion protein corresponding to full length human CCND2.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 894
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a