CCND3, Mouse, Clone: DCS22, Abnova™

Catalog No.	Quantity
89-110-669	100 μg

Catalog No. 89-110-669 Supplier Abnova Corporation Supplier No. MAB1853

Description

Mouse monoclonal antibody raised against full-length recombinant CCND3.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CCND3
• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: DCS22
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant CCND3.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.08% sodium azide)
• Gene: CCND3
• Gene Symbols: CCND3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human CCND3.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 896
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1