CD14, Mouse, Clone: biG 13, Abnova™

Mouse monoclonal antibody raised against CD14.

Supplier:  Abnova Corporation MAB5654

Catalog No. 89-112-345

Description

CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq

Specifications

• Antigen: CD14
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (1:5000) The optimal working dilution should be determined by the end user.
• Gene: CD14
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: biG 13 represents an excellent marker for CD14. CD14 has been shown to be involved in LPS-induced cell activation. This antigen is present as a membrane bound form and as a soluble antigen, both of which are involved in cell stimulation by LPS. The plasma protein LBP plays an important role in the LPS-CD14 mediated cell activation. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for Endotoxin.
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: biG 13
• Description: Mouse monoclonal antibody raised against CD14.
• Formulation: Lyophilized from PBS
• Gene Symbols: CD14
• Immunogen: Monocytes of different species and immunoaffinity purified soluble human CD14.
• Regulatory Status: RUO
• Gene ID (Entrez): 929
• Target Species: Bovine, Canine, Equine, Human, Pig
• Form: Lyophilized