CD180, Mouse, PE, Clone: G28-8, Abnova™

Catalog No.	Quantity
89-108-444	100 Reactions

Catalog No. 89-108-444 Supplier Abnova Corporation Supplier No. MAB10239

Description

Mouse monoclonal antibody raised against of CD180.

CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq

Specifications

• Antigen: CD180
• Applications: Flow Cytometry, Functional Assay, Immunoprecipitation
• Classification: Monoclonal
• Clone: G28-8
• Conjugate: PE
• Description: Mouse monoclonal antibody raised against of CD180.
• Dilution: Flow Cytometry (20 uL reagent/100 uL of whole blood or 10⁶ cells) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: CD180
• Gene Alias: LY64/Ly78/MGC126233/MGC126234/RP105
• Gene Symbols: CD180
• Host Species: Mouse
• Immunogen: Human tonsillar B cells.
• Purification Method: Size-exclusion chromatography purification
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4064
• Test Specificity: CD180, a TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
• Form: Liquid
• Isotype: IgG1