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MilliporeSigma™ Mouse anti-CD19, Clone: SJ25C1, PE,

Catalog No. MABF1650 Shop All MilliporeSigma Products
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25 Tests
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MABF1650 25 Tests
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Catalog No. MABF1650 Supplier MilliporeSigma™ Supplier No. MABF1650
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Description

Mouse Monoclonal Antibody

Specifically detects CD19 clone: SJ25C1 in Human samples, and it is validated for Flow Cytometry

The SJ25C1 antibody reacts with human CD19, a 95kDa glycoprotein which acts as a co-receptor, along with CD21 (CR2), CD81 (TAPA-1) and CD225 (Leu13), in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. Upon activation and tyrosine phosphorylation, the CD19 molecule can provide an anchor for cytoplasmic signaling proteins such as GRB2, SOS or PLCG2. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The SJ25C1 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD19
Applications Flow Cytometry
Classification Monoclonal
Clone SJ25C1
Conjugate PE
Formulation Purified Mouse monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Accession No. P15391
Gene Symbols CD19
Host Species Mouse
Immunogen Immunogen information for this antibody is proprietary information.
Purification Method Purified by size-exclusion chromatography
Quantity 25 Tests
Regulatory Status RUO
Research Discipline Inflammation and Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt. Note: It is recommended to store the product undiluted at 2°C to 8°C and protected from prolonged exposure to light. Do not freeze.
Form Purified
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For Research Use Only

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