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CD1A, Mouse, Clone: HI149, Abnova™

Catalog No. 89108269 Shop All Abnova Corporation Products
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89-108-269 100 μg
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Catalog No. 89-108-269 Supplier Abnova Corporation Supplier No. MAB0941
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Description

Mouse monoclonal antibody raised against native CD1A.

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq

Specifications

Antigen CD1A
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone HI149
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native CD1A.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.09% sodium azide)
Gene CD1A
Gene Alias CD1/FCB6/HTA1/R4/T6
Gene Symbols CD1A
Host Species Mouse
Immunogen Native purified CD1A from human thymocytes.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 909
Test Specificity This antibody reacts with CD1a (T6), a 49 KDa polypeptide associated with beta2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas. This antibody does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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