Mouse anti-CD1b, Clone: 100-1A5, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2452430.2MG

Catalog No. NBP24524302

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD1b Monoclonal antibody specifically detects CD1b in Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

• Antigen: CD1b
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
• Gene Accession No.: P29016
• Gene Symbols: CD1B
• Immunogen: Stimulated human leukocytes
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
• Content And Storage: Store at 4C.
• Isotype: IgM κ

• Applications: Flow Cytometry, Immunofluorescence
• Clone: 100-1A5
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: CD1, CD1A, CD1b antigen, CD1B antigen, b polypeptide, CD1b molecule, cortical thymocyte antigen CD1B, differentiation antigen CD1-alpha-3, MGC125990, MGC125991, R1, T-cell surface glycoprotein CD1b
• Host Species: Mouse
• Molecular Weight of Antigen: 44 kDa
• Quantity: 0.2 mg
• Research Discipline: Immunology
• Gene ID (Entrez): 910
• Target Species: Human
• Form: Purified

For Research Use Only