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Description
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | CD247 |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry |
| Classification | Monoclonal |
| Clone | 4D10A6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant CD247. |
| Dilution | Immunohistochemistry (1:200-1:400) ELISA (1:10000) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from PBS |
| Gene | CD247 |
| Gene Alias | CD3-ZETA/CD3H/CD3Q/CD3Z/T3Z/TCRZ |
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