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Description
The OX-39 monoclonal antibody specifically b inds to the α chain of the IL-2 R eceptor (IL-2R α , IL2RA) on activated T cells, T regulatory cells, and thymic and splenic dendritic cells. CD25 has also been detected on rat intestinal epithelial cells. It has been reported that OX-39 mAb weakly blocks binding of IL-2 to T-cell blasts and that it blocks IL-2 stimulated epithelial cell migration in an in vitro model of wound healing.
Specifications
Specifications
| Antigen | CD25 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | OX-39 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 421 |
| Description | Interleukin-2 receptor alpha chain; IL-2RA; IL-2Rα; Il2ra; IL-2R p55 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Rat T blasts from mixed-lymphocyte reactions |
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