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CD27 Mouse anti-Human, APC-R700, Clone: M-T271, BD

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BDB565116 100 Tests
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Catalog No. BDB565116 Supplier BD Biosciences Supplier No. 565116
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Description

Mouse Monoclonal Antibody

The M-T271 monoclonal antibody specifically binds to CD27. CD27 presents as a type I transmembrane, disulphide-linked 110 kDa homodimer comprised of two polypeptide chains. The CD27 molecule is a lymphocyte-specific member of the TNF/NGF-R family, and is expressed on a subset of human thymocytes and on the majority of mature T lymphocytes, activated B cells and NK cells. CD27 is highly induced on T cells after TCR stimulation. CD27 binds to CD70 (also known as, CD27 ligand or CD27L) and may be involved in cellular interaction of T and B lymphocytes.

This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700. APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness. This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD27
Applications Flow Cytometry
Classification Monoclonal
Clone M-T271
Conjugate APC-R700
Description TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152
Formulation Aqueous buffered solution containing BSA, protein stabilizer, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human T-CLL cells
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 939
Target Species Baboon, Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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