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CD3, Mouse, Clone: 33-2A3, Abnova™

Catalog No. 89135888 Shop All Abnova Corporation Products
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89-135-888 100 μg
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Catalog No. 89-135-888 Supplier Abnova Corporation Supplier No. MAB4959
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Description

Mouse monoclonal antibody raised against native CD3.

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq

Specifications

Antigen CD3
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry
Classification Monoclonal
Clone 33-2A3
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native CD3.
Dilution Flow Cytometry (20 uL/106 cells) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
Gene CD3E
Gene Alias FLJ18683/T3E/TCRE
Gene Symbols CD3E
Host Species Mouse
Immunogen Human leucocytes.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 916
Target Species Human
Content And Storage Store in the dark at 4°C. Avoid prolonged exposure to light.
Form Liquid
Isotype IgG2a
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