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CD307c Mouse anti-Human, Biotin, Clone: H5, BD

Catalog No. BDB565056 Shop All BD Biosciences Products
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BDB565056 100 Tests
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Catalog No. BDB565056 Supplier BD Biosciences Supplier No. 565056
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Description

Mouse Monoclonal Antibody

The H5 monoclonal antibody specifically binds to CD307c which is also known as Fc receptor-like 3 (FCRL3), Immune receptor translocation-associated protein 3 (IRTA3), IFGP family protein 3 (IFGP3), and SH2 domain-containing phosphatase anchor protein 2 (SPAP2). The FCRL3 gene is present in humans but not in mice. CD307c is a type I transmembrane glycoprotein that belongs to the FCRL family within the Ig gene superfamily. CD307c shares sequence homology with classical the Fc receptors. CD307c is expressed on subsets of B cells, plasma cells, NK cells, CD8+ T cells, and CD4+ natural T regulatory cells. CD307c isoforms contain multiple extracellular Ig domains and immunoreceptor-tyrosine activation (ITAM) and inhibitory (ITIM) motifs in their intracellular domains. CD307c may be involved in the regulation of immune responses. Genetic variation in FCRL3 has been associated with susceptibility to certain autoimmune diseases.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD307c
Applications Flow Cytometry
Classification Monoclonal
Clone H5
Conjugate Biotin
Description FCRL3; Fc receptor-like 3; FcRH3; IRTA3; IFGP3; hIFGP3; SPAP2
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Recombinant Human FCRL3
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2b κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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