CD31 Mouse anti-Human, BUV395, Clone: WM59, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 565290

Catalog No. BDB565290

Description

The WM59 monoclonal antibody specifically binds to platelet endothelial cell adhesion molecule-1, (PECAM-1, PECAM1), which is also known as GPIIA', or EndoCAM. CD31 is a 130 kDa type I transmembrane glycoprotein that belongs to the Ig gene superfamily. CD31 has wide tissue distribution and is expressed on platelets, monocytes, granulocytes, NK cells, T cell subsets, and in high amounts on endothelial cells. CD31 functions as a vascular endothelial cell adhesion molecule and is involved in the transendothelial migration of leucocytes in inflammatory responses. It may also be involved in thrombosis, angiogenesis, and wound healing.

The antibody was conjugated to BD Horizon BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

Specifications

• Antigen: CD31
• Classification: Monoclonal
• Conjugate: Brilliant Ultraviolet 395
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 5175
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: WM59
• Description: EndoCAM; GPIIA; PECA1; PECAM1; Platelet endothelial cell adhesion molecule
• Host Species: Mouse
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ