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CD32 Mouse anti-Human, Brilliant Violet 421, Clone: FLI8.26, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564838

Catalog No. BDB564838


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Description

Description

The FLI8.26 monoclonal antibody specifically recognizes CD32 which is also known as Fcγreceptor type II (FcγRII). CD32 is a type I transmembrane glycoprotein that serves as a low affinity receptor for aggregated IgG. The FLI8.26 antibody recognizes a, b, and c forms of CD32 that are encoded by separate genes: CD32a/ FcγRIIa ( FCGR2A ), CD32b/ FcγRIIb ( FCGR2B ). These forms are differentially expressed on monocytes, granulocytes, T cells, B cells, NK cells, or platelets. These receptors play various roles in mediating and regulating inflammation and immunity including phagocytosis, cytotoxicity, degranulation, or platelet activation.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

Specifications

CD32
FLI8.26
CD32a,FcγRIIa, FCGR2A; CD32b, FcγRIIb, FCGR2B; CD32c, FcγRIIc, FCGR2C
Affinity Purified
K562 or FcγRII+ L cell lines
Affinity Chromatography
RUO
Primary
Baboon, Cynomolgus, Human, Rhesus
Flow Cytometry
Brilliant Violet 421
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG2b, κ
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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