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CD35 Mouse anti-Human, Alexa Fluor 647, Clone: E11, BD

Catalog No. BDB565329 Shop All BD Biosciences Products
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BDB565329 50 Tests
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Catalog No. BDB565329 Supplier BD Biosciences Supplier No. 565329

Description

Mouse Monoclonal Antibody

The E11 monoclonal antibody specifically binds to CD35. CD35 is also known as Complement receptor type 1 (CR1), C3b/C4b receptor, C3BR, C4BR, Immune adherence receptor, or KN. CD35 is a type I transmembrane glycoprotein that exists in four allelic forms of 160, 190, 220 and 250 kDa. CD35 serves as a receptor for complement fragments C3b, iC3b, C3dg, C4b, iC3, and iC4. It enhances phagocytosis by neutrophils and monocytes and regulates complement activation. It is expressed on erythrocytes, granulocytes, monocytes, B cells, and some dendritic cells, T cells, and NK cells. It binds complement components C3b and C4b, mediating. This antibody cannot inhibit the phagocytic capacity of granulocytes. The CD35 antibody is useful in studies of cells that express complement receptors.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD35
Applications Flow Cytometry
Classification Monoclonal
Clone E11
Conjugate Alexa Fluor 647
Description CR1; Complement receptor type 1; C3b/C4b receptor; C3BR; C4BR; KN
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Cells of the Monocyte Lineage
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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